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TitleA steric block in translation caused by the antibiotic spectinomycin.
Journal, issue, pagesAcs Chem. Biol., Vol. 2, Page 545-552, Year 2007
Publish dateJul 21, 2007 (structure data deposition date)
AuthorsBorovinskaya, M.A. / Shoji, S. / Holton, J.M. / Fredrick, K. / Cate, J.H.
External linksAcs Chem. Biol. / PubMed:17696316
MethodsX-ray diffraction
Resolution3.5 - 3.93 Å
Structure data

PDB-4v56:
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin.
Method: X-RAY DIFFRACTION / Resolution: 3.93 Å

PDB-4v57:
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin.
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-SCM:
SPECTINOMYCIN / antibiotic*YM

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NMY:
NEOMYCIN / antibiotic*YM

Source
  • escherichia coli (E. coli)
KeywordsRIBOSOME / RNA-protein complex / Ribonucleoprotein / Ribosomal protein / RNA-binding / rRNA-binding / Antibiotic resistance / Repressor / Transcription / Transcription regulation / Transcription termination / Translation regulation / Acetylation / tRNA-binding / Methylation / Endonuclease / Hydrolase / Nuclease

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