+Search query
-Structure paper
Title | Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis. |
---|---|
Journal, issue, pages | Cancer Res., Vol. 76, Page 724-, Year 2016 |
Publish date | Aug 29, 2014 (structure data deposition date) |
Authors | Marusiak, A.A. / Stephenson, N.L. / Baik, H. / Trotter, E.W. / Li, Y. / Blyth, K. / Mason, S. / Chapman, P. / Puto, L.A. / Read, J.A. ...Marusiak, A.A. / Stephenson, N.L. / Baik, H. / Trotter, E.W. / Li, Y. / Blyth, K. / Mason, S. / Chapman, P. / Puto, L.A. / Read, J.A. / Brassington, C. / Pollard, H.K. / Phillips, C. / Green, I. / Overman, R. / Collier, M. / Testoni, E. / Miller, C. / Hunter, T. / Sansom, O.J. / Brognard, J. |
External links | Cancer Res. / PubMed:26637668 |
Methods | X-ray diffraction |
Resolution | 2.8 - 2.81 Å |
Structure data | PDB-4uy9: PDB-4uya: |
Chemicals | ChemComp-HOH: ChemComp-AGS: ChemComp-MG: |
Source |
|
Keywords | TRANSFERASE / MLK FAMILY / MLK1 AND MLK3 SUBTYPE / ATP-BINDING / KINASE / NUCLEOTIDE-BINDING / PHOSPHOPROTEIN / SERINE/THREONINE-PROTEIN KINASE / SH3 DOMAIN / MIXED-LINEAGE KINASE / LEUCINE ZIPPER 1 |