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-Structure paper
Title | Synthesis, Structure, and SAR of Tetrahydropyran-Based LpxC Inhibitors. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 5, Page 1213-1218, Year 2014 |
Publish date | Jul 19, 2014 (structure data deposition date) |
Authors | Murphy-Benenato, K.E. / Olivier, N. / Choy, A. / Ross, P.L. / Miller, M.D. / Thresher, J. / Gao, N. / Hale, M.R. |
External links | Acs Med. Chem. Lett. / PubMed:25408833 |
Methods | X-ray diffraction |
Resolution | 1.25 - 1.34 Å |
Structure data | PDB-4u3b: PDB-4u3d: |
Chemicals | ChemComp-IMD: ChemComp-ZN: ChemComp-CL: ChemComp-3BW: ChemComp-HOH: ChemComp-3BX: |
Source |
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Keywords | HYDROLASE / antibacterial / lpxc / gram negative bacteria / MMP / hydrophobe |