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TitleDiscovery of substrate selective, ATP-competitive P38 alpha MAP kinase inhibitors
Journal, issue, pagesTo Be Published
Publish dateJul 8, 2014 (structure data deposition date)
AuthorsCumming, J.G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-4tyh:
Ternary complex of P38 and MK2 with a P38 inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-39G:
N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsTransferase/Transferase inhibitor / P38 / MK2 / P38 inhibitor / Transferase-Transferase inhibitor complex

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