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-Structure paper
Title | Selective inhibitors of the FK506-binding protein 51 by induced fit. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 11, Page 33-37, Year 2015 |
Publish date | Jun 30, 2014 (structure data deposition date) |
![]() | Gaali, S. / Kirschner, A. / Cuboni, S. / Hartmann, J. / Kozany, C. / Balsevich, G. / Namendorf, C. / Fernandez-Vizarra, P. / Sippel, C. / Zannas, A.S. ...Gaali, S. / Kirschner, A. / Cuboni, S. / Hartmann, J. / Kozany, C. / Balsevich, G. / Namendorf, C. / Fernandez-Vizarra, P. / Sippel, C. / Zannas, A.S. / Draenert, R. / Binder, E.B. / Almeida, O.F. / Ruhter, G. / Uhr, M. / Schmidt, M.V. / Touma, C. / Bracher, A. / Hausch, F. |
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Methods | X-ray diffraction |
Resolution | 1.25 - 3.003 Å |
Structure data | ![]() PDB-4tw6: ![]() PDB-4tw7: ![]() PDB-4tw8: |
Chemicals | ![]() ChemComp-37L: ![]() ChemComp-GOL: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-37K: ![]() ChemComp-37M: |
Source |
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![]() | ISOMERASE / Fk-506 binding domain / Hsp90 cochaperone / immunophiline / peptidyl-prolyl isomerase / ligand selectivity |