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-Structure paper
Title | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 9, Page 2508-2516, Year 2014 |
Publish date | Aug 21, 2014 (structure data deposition date) |
![]() | Leu, J.I. / Zhang, P. / Murphy, M.E. / Marmorstein, R. / George, D.L. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.7469 - 3.4501 Å |
Structure data | ![]() PDB-4r5g: ![]() PDB-4r5i: ![]() PDB-4r5j: ![]() PDB-4r5k: ![]() PDB-4r5l: |
Chemicals | ![]() ChemComp-3JE: ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() ChemComp-PO4: ![]() ChemComp-CA: |
Source |
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![]() | Chaperone/Chaperone inhibitor / Helical bundle / beta sheets / Chaperone / HSP70/DnaK inhibitors / membrane / Chaperone-Chaperone inhibitor complex / Substrate Binding |