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-Structure paper
Title | Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. F, Vol. 70, Page 1143-1149, Year 2014 |
Publish date | May 12, 2014 (structure data deposition date) |
Authors | Aoyagi-Scharber, M. / Gardberg, A.S. / Yip, B.K. / Wang, B. / Shen, Y. / Fitzpatrick, P.A. |
External links | Acta Crystallogr. ,Sect. F / PubMed:25195882 |
Methods | X-ray diffraction |
Resolution | 2.35 - 2.5 Å |
Structure data | PDB-4pjt: PDB-4pjv: |
Chemicals | ChemComp-SO4: ChemComp-2YQ: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / PARP1 / Inhibitor / Complex / TRANSFERASE-TRANSFERASE INHIBITOR complex / PARP2 |