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-Structure paper
Title | Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. F, Vol. 70, Page 1143-1149, Year 2014 |
Publish date | May 12, 2014 (structure data deposition date) |
![]() | Aoyagi-Scharber, M. / Gardberg, A.S. / Yip, B.K. / Wang, B. / Shen, Y. / Fitzpatrick, P.A. |
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Methods | X-ray diffraction |
Resolution | 2.35 - 2.5 Å |
Structure data | ![]() PDB-4pjt: ![]() PDB-4pjv: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-2YQ: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / PARP1 / Inhibitor / Complex / TRANSFERASE-TRANSFERASE INHIBITOR complex / PARP2 |