EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder.
ジャーナル・号・ページ	J. Mol. Biol., Vol. 427, Page 2396-2409, Year 2015
掲載日	2014年2月5日 (構造データの登録日)
著者	Dellus-Gur, E. / Elias, M. / Caselli, E. / Prati, F. / Salverda, M.L. / de Visser, J.A. / Fraser, J.S. / Tawfik, D.S.
リンク	J. Mol. Biol. / PubMed:26004540
手法	X線回折
解像度	1.05 - 2.4 Å
構造データ	PDB-4op5: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation 手法: X-RAY DIFFRACTION / 解像度: 1.05 Å PDB-4op8: Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-4opq: Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutations 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-4opr: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-4opy: Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-4opz: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation in complex with boron-based inhibitor EC25 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-4oq0: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutation in complex with boron-based inhibitor EC25 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-4oqg: Crystal structure of TEM-1 beta-lactamase in complex with boron-based inhibitor EC25 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4oqh: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation in complex with boron-based inhibitor EC25 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-4oqi: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutations 手法: X-RAY DIFFRACTION / 解像度: 1.13 Å
化合物	ChemComp-CA: Unknown entry / カルシウムジカチオン ChemComp-PG4: TETRAETHYLENE GLYCOL / テトラエチレングリコ-ル / 沈殿剤YM ChemComp-MES: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID / 2-モルホリノエタンスルホン酸 / pH緩衝剤YM ChemComp-HOH: WATER ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-2UL: 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid ChemComp-ACT: ACETATE ION / 酢酸イオン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-ZN: Unknown entry
由来	escherichia coli (大腸菌)
キーワード	HYDROLASE / Beta-lactamase / Beta-lactamas / hydrolase/hydrolase inhibitor / hydrolase-hydrolase inhibitor complex / Beta-lctamase