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-Structure paper
Title | Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 24, Page 1484-1488, Year 2014 |
Publish date | Feb 7, 2014 (structure data deposition date) |
Authors | Petros, A.M. / Swann, S.L. / Song, D. / Swinger, K. / Park, C. / Zhang, H. / Wendt, M.D. / Kunzer, A.R. / Souers, A.J. / Sun, C. |
External links | Bioorg. Med. Chem. Lett. / PubMed:24582986 |
Methods | X-ray diffraction |
Resolution | 1.81 - 2.86 Å |
Structure data | PDB-4oq5: PDB-4oq6: |
Chemicals | ChemComp-2UU: ChemComp-HOH: ChemComp-2UV: |
Source |
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Keywords | APOPTOSIS/INHIBITOR / APOPTOSIS-INHIBITOR complex |