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-Structure paper
Title | AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter. |
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Journal, issue, pages | Elife, Vol. 3, Page e02375-e02375, Year 2014 |
Publish date | Jan 16, 2014 (structure data deposition date) |
Authors | Schulze-Gahmen, U. / Lu, H. / Zhou, Q. / Alber, T. |
External links | Elife / PubMed:24843025 |
Methods | X-ray diffraction |
Resolution | 3 Å |
Structure data | PDB-4ogr: |
Chemicals | ChemComp-ADN: ChemComp-ZN: ChemComp-HOH: |
Source |
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Keywords | transferase/viral protein / P-TEFb / cyclin-dependent kinase 9 / cyclin fold / intrinsically unstructured AFF4 / transcriptional regulation at HIV promoter / binds TAR / N-terminal acetylation of Tat / transferase-viral protein complex |