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-Structure paper
Title | Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 58, Page 6861-6869, Year 2014 |
Publish date | Jan 7, 2014 (structure data deposition date) |
![]() | Lam, A.M. / Edwards, T.E. / Mosley, R.T. / Murakami, E. / Bansal, S. / Lugo, C. / Bao, H. / Otto, M.J. / Sofia, M.J. / Furman, P.A. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-4obc: |
Chemicals | ![]() ChemComp-MES: ![]() ChemComp-GOL: ![]() ChemComp-PG6: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | Viral Protein / transferase / Hepatitis / HCV / viral polymerase / RNA-dependent-RNA-polymerase / RdRp / resistance / nucleotide analog inhibitor |