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Structure paper

TitleMolecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors.
Journal, issue, pagesJ. Steroid Biochem. Mol. Biol., Vol. 144PB, Page 427-435, Year 2014
Publish dateJan 6, 2014 (structure data deposition date)
AuthorsPetit-Topin, I. / Fay, M. / Resche-Rigon, M. / Ulmann, A. / Gainer, E. / Rafestin-Oblin, M.E. / Fagart, J.
External linksJ. Steroid Biochem. Mol. Biol. / PubMed:25204619
MethodsX-ray diffraction
Resolution2.41 Å
Structure data

PDB-4oar:
Progesterone receptor with bound ulipristal acetate and a peptide from the co-repressor SMRT
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-2S0:
[(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopen / medication*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/Peptide / PROGESTERONE RECEPTOR / STEROID RECEPTOR / NUCLEAR RECEPTOR / TRANSCRIPTION FACTOR / WOMEN HEALTH / CONTRACEPTION / TRANSCRIPTION-Peptide complex

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