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TitleCrystal Structure of TTK kinase domain with an inhibitor: 401498
Journal, issue, pagesTO BE PUBLISHED
Publish dateDec 22, 2013 (structure data deposition date)
AuthorsQiu, W. / Plotnikova, O. / Feher, M. / Awrey, D.E. / Chirgadze, N.Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.38 Å
Structure data

PDB-4o6l:
Crystal Structure of TTK kinase domain with an inhibitor: 401498 (N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide)
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

Chemicals

ChemComp-2QK:
N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / Kinase / TTK / inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex

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