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-Structure paper
Title | Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. |
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Journal, issue, pages | J. Biol. Chem., Vol. 289, Page 33557-33567, Year 2014 |
Publish date | Dec 6, 2013 (structure data deposition date) |
Authors | Bowers, P.M. / Verdino, P. / Wang, Z. / da Silva Correia, J. / Chhoa, M. / Macondray, G. / Do, M. / Neben, T.Y. / Horlick, R.A. / Stanfield, R.L. ...Bowers, P.M. / Verdino, P. / Wang, Z. / da Silva Correia, J. / Chhoa, M. / Macondray, G. / Do, M. / Neben, T.Y. / Horlick, R.A. / Stanfield, R.L. / Wilson, I.A. / King, D.J. |
External links | J. Biol. Chem. / PubMed:25320089 |
Methods | X-ray diffraction |
Resolution | 1.602 - 1.75 Å |
Structure data | PDB-4nwt: PDB-4nwu: |
Chemicals | ChemComp-MES: ChemComp-ACT: ChemComp-PGE: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / beta sandwich / human beta nerve growth factor / beta-sandwich |