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TitleHow HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Journal, issue, pagesElife, Vol. 3, Page e01754-e01754, Year 2014
Publish dateOct 29, 2013 (structure data deposition date)
AuthorsRen, X. / Park, S.Y. / Bonifacino, J.S. / Hurley, J.H.
External linksElife / PubMed:24473078
MethodsX-ray diffraction
Resolution2.8841 Å
Structure data

PDB-4nee:
crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef
Method: X-RAY DIFFRACTION / Resolution: 2.8841 Å

Source
  • rattus norvegicus (Norway rat)
  • human immunodeficiency virus 1
KeywordsVIRAL PROTEIN/PROTEIN TRANSPORT / clathrin Adaptor AP-2 / HIV-1 Nef / CD4 downregulation / VIRAL PROTEIN-PROTEIN TRANSPORT complex

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