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-Structure paper
Title | Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 9693-9700, Year 2013 |
Publish date | Aug 29, 2013 (structure data deposition date) |
![]() | Zhang, W. / McIver, A.L. / Stashko, M.A. / DeRyckere, D. / Branchford, B.R. / Hunter, D. / Kireev, D. / Miley, M.J. / Norris-Drouin, J. / Stewart, W.M. ...Zhang, W. / McIver, A.L. / Stashko, M.A. / DeRyckere, D. / Branchford, B.R. / Hunter, D. / Kireev, D. / Miley, M.J. / Norris-Drouin, J. / Stewart, W.M. / Lee, M. / Sather, S. / Zhou, Y. / Di Paola, J.A. / Machius, M. / Janzen, W.P. / Earp, H.S. / Graham, D.K. / Frye, S.V. / Wang, X. |
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Methods | X-ray diffraction |
Resolution | 2.51 - 2.59 Å |
Structure data | ![]() PDB-4mh7: ![]() PDB-4mha: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-MG: ![]() ChemComp-MH7: ![]() ChemComp-HOH: ![]() ChemComp-4MH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / TYROSINE KINASE / ACUTE LYMPHOBLASTIC LEUKEMIA / RATIONAL STRUCTURE BASED DRUG DESIGN / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX / RATIONAL STRUCTURE-BASED DRUG DESIGN |