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-Structure paper
Title | Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 21, Page 5725-5737, Year 2013 |
Publish date | Jun 27, 2013 (structure data deposition date) |
Authors | Asano, M. / Hashimoto, K. / Saito, B. / Shiokawa, Z. / Sumi, H. / Yabuki, M. / Yoshimatsu, M. / Aoyama, K. / Hamada, T. / Morishita, N. ...Asano, M. / Hashimoto, K. / Saito, B. / Shiokawa, Z. / Sumi, H. / Yabuki, M. / Yoshimatsu, M. / Aoyama, K. / Hamada, T. / Morishita, N. / Dougan, D.R. / Mol, C.D. / Yoshida, S. / Ishikawa, T. |
External links | Bioorg. Med. Chem. / PubMed:23928071 |
Methods | X-ray diffraction |
Resolution | 1.55 - 2 Å |
Structure data | PDB-4lge: PDB-4lgu: |
Chemicals | ChemComp-ZN: ChemComp-1Y0: ChemComp-HOH: ChemComp-1YH: |
Source |
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Keywords | Ligase/Ligase inhibitor / lAP family / 3 BIR repeats / 1 CARD domain / 1 RING-type zinc finger / Ligase-Ligase inhibitor complex / CARD domain |