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TitleX-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
Journal, issue, pagesJ. Med. Chem., Vol. 56, Page 4758-4763, Year 2013
Publish dateMay 8, 2013 (structure data deposition date)
AuthorsMolodtsov, V. / Nawarathne, I.N. / Scharf, N.T. / Kirchhoff, P.D. / Showalter, H.D. / Garcia, G.A. / Murakami, K.S.
External linksJ. Med. Chem. / PubMed:23679862
MethodsX-ray diffraction
Resolution3.686 - 3.965 Å
Structure data

PDB-4kmu:
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin
Method: X-RAY DIFFRACTION / Resolution: 3.85 Å

PDB-4kn4:
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2b
Method: X-RAY DIFFRACTION / Resolution: 3.965 Å

PDB-4kn7:
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2c
Method: X-RAY DIFFRACTION / Resolution: 3.686 Å

Chemicals

ChemComp-RFP:
RIFAMPICIN / antibiotic*YM

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-1RL:
Benzoxazinorifamycin-2b

ChemComp-1RM:
Benzoxazinorifamycin-2c

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE/ANTIBIOTIC / transcription / DNA / RNA / TRANSFERASE-ANTIBIOTIC complex

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