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TitleNovel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 69, Page 352-366, Year 2013
Publish dateApr 24, 2013 (structure data deposition date)
AuthorsChin, K.H. / Tu, Z.L. / Su, Y.C. / Yu, Y.J. / Chen, H.C. / Lo, Y.C. / Chen, C.P. / Barber, G.N. / Chuah, M.L. / Liang, Z.X. / Chou, S.H.
External linksActa Crystallogr. ,Sect. D / PubMed:23519410
MethodsX-ray diffraction
Resolution2.2 - 2.36 Å
Structure data

PDB-4kby:
mSTING/c-di-GMP
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

PDB-4kc0:
mSTING
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-C2E:
9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / mouse STING / c-di-GMP

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