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-Structure paper
Title | Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 17832-17837, Year 2013 |
Publish date | Apr 19, 2013 (structure data deposition date) |
Authors | Reshetnyak, A.V. / Nelson, B. / Shi, X. / Boggon, T.J. / Pavlenco, A. / Mandel-Bausch, E.M. / Tome, F. / Suzuki, Y. / Sidhu, S.S. / Lax, I. / Schlessinger, J. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:24127596 |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.7 Å |
Structure data | PDB-4k94: PDB-4k9e: |
Chemicals | ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / receptor tyrosine kinase (RTK) / Fab / Ig SF / IgG |