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Structure paper

TitleThe structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Journal, issue, pagesSci Rep, Vol. 4, Page 4145-4145, Year 2014
Publish dateMar 14, 2013 (structure data deposition date)
AuthorsLi, J. / Wang, C. / Zhang, Z.M. / Cheng, Y.Q. / Zhou, J.
External linksSci Rep / PubMed:24553401
MethodsX-ray diffraction
Resolution1.9 - 2 Å
Structure data

PDB-4jn9:
Crystal structure of the DepH
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4jna:
Crystal structure of the DepH complex with dimethyl-FK228
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • chromobacterium violaceum (bacteria)
KeywordsOXIDOREDUCTASE / disulfide bond formation / FK228 / depsipeptide / FAD-dependent oxidoreductase / Oxidoreductase/Oxidoreductase inhibitor / Oxidoreductase-Oxidoreductase inhibitor complex

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