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-Structure paper
Title | Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 14924-14929, Year 2013 |
Publish date | Feb 26, 2013 (structure data deposition date) |
![]() | Sha, F. / Gencer, E.B. / Georgeon, S. / Koide, A. / Yasui, N. / Koide, S. / Hantschel, O. |
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Methods | X-ray diffraction |
Resolution | 2.3 - 2.31 Å |
Structure data | ![]() PDB-4je4: ![]() PDB-4jeg: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | Signaling protein/protein binding / engineered binding protein / SHP2 SH2-monobody complex / Phosphatase / Phosphotyrosine Binding / Phosphorylation / Signaling protein-protein binding complex |