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Structure paper

TitleStructural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 11343-11348, Year 2013
Publish dateDec 28, 2012 (structure data deposition date)
AuthorsDoki, S. / Kato, H.E. / Solcan, N. / Iwaki, M. / Koyama, M. / Hattori, M. / Iwase, N. / Tsukazaki, T. / Sugita, Y. / Kandori, H. ...Doki, S. / Kato, H.E. / Solcan, N. / Iwaki, M. / Koyama, M. / Hattori, M. / Iwase, N. / Tsukazaki, T. / Sugita, Y. / Kandori, H. / Newstead, S. / Ishitani, R. / Nureki, O.
External linksProc. Natl. Acad. Sci. USA / PubMed:23798427
MethodsX-ray diffraction
Resolution1.9 - 2.4 Å
Structure data

PDB-4ikv:
Crystal structure of peptide transporter POT
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4ikw:
Crystal structure of peptide transporter POT in complex with sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.004 Å

PDB-4ikx:
Crystal structure of peptide transporter POT (E310Q mutant)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4iky:
Crystal structure of peptide transporter POT (E310Q mutant) in complex with sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4ikz:
Crystal structure of peptide transporter POT (E310Q mutant) in complex with alafosfalin
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-OLA:
OLEIC ACID

ChemComp-OLB:
(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-AFS:
N-[(1R)-1-phosphonoethyl]-L-alaninamide / antifungal, antibiotic*YM

Source
  • geobacillus kaustophilus (bacteria)
KeywordsTRANSPORT PROTEIN / major facilitator superfamily

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