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-Structure paper
Title | X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 135, Page 11708-11711, Year 2013 |
Publish date | Nov 2, 2012 (structure data deposition date) |
![]() | Zhu, J. / Yang, Q. / Dai, D. / Huang, Q. |
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Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | ![]() PDB-4htx: ![]() PDB-4htz: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-MG: ![]() ChemComp-19F: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / Hydrolase / HYDROLASE-HYDROLASE INHIBITOR complex |