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Structure paper

TitleA Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1
Journal, issue, pagesTO BE PUBLISHED
Publish dateSep 28, 2012 (structure data deposition date)
AuthorsSpringer, T. / Yu, Y. / Zhu, J. / Wang, J.-H. / Huang, P.-S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.4 - 2.871 Å
Structure data

PDB-4hbq:
Crystal structure of a loop deleted mutant of Human MAdCAM-1 D1D2
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-4hc1:
Crystal structure of a loop deleted mutant of human MAdCAM-1 D1D2 complexed with Fab 10G3
Method: X-RAY DIFFRACTION / Resolution: 2.871 Å

PDB-4hcr:
Crystal structure of human MAdCAM-1 D1D2 complexed with Fab PF-547659
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4hd9:
Crystal structure of native human MAdCAM-1 D1D2 domain
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / immunoglobulin superfamily / integrin alpha4beta7 / rolling and firm adhesion

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