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-Structure paper
Title | Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase. |
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Journal, issue, pages | J. Med. Chem., Vol. 55, Page 10272-10276, Year 2012 |
Publish date | Mar 7, 2012 (structure data deposition date) |
Authors | Carosati, E. / Tochowicz, A. / Marverti, G. / Guaitoli, G. / Benedetti, P. / Ferrari, S. / Stroud, R.M. / Finer-Moore, J. / Luciani, R. / Farina, D. ...Carosati, E. / Tochowicz, A. / Marverti, G. / Guaitoli, G. / Benedetti, P. / Ferrari, S. / Stroud, R.M. / Finer-Moore, J. / Luciani, R. / Farina, D. / Cruciani, G. / Costi, M.P. |
External links | J. Med. Chem. / PubMed:23075414 |
Methods | X-ray diffraction |
Resolution | 2.302 Å |
Structure data | PDB-4e28: |
Chemicals | ChemComp-SO4: ChemComp-0MZ: ChemComp-9MZ: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Human Thymidylate Synthase (hTS) inactive conformation / hTS-Inhibitor complex / TRANSFERASE-TRANSFERASE INHIBITOR complex |