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Title | Molecular Basis for the Anti-Parasitic Activity of a Mercaptoacetamide Derivative that Inhibits Histone Deacetylase 8 (Hdac8) from the Human Pathogen Schistosoma Mansoni |
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Journal, issue, pages | J. Mol. Biol., Vol. 426, Page 3442-, Year 2014 |
Publish date | Feb 14, 2014 (structure data deposition date) |
![]() | Stolfa, D.A. / Marek, M. / Lancelot, J. / Hauser, A.T. / Walter, A. / Leproult, E. / Melesina, J. / Rumpf, T. / Wurtz, J.M. / Cavarelli, J. ...Stolfa, D.A. / Marek, M. / Lancelot, J. / Hauser, A.T. / Walter, A. / Leproult, E. / Melesina, J. / Rumpf, T. / Wurtz, J.M. / Cavarelli, J. / Sippl, W. / Pierce, R.J. / Romier, C. / Jung, M. |
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Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | ![]() PDB-4cqf: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-K: ![]() ChemComp-9Z8: ![]() ChemComp-DMF: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / STRUCTURAL PROTEIN / EUKARYOTES / PLATYHELMINTHS / EPIGENETICS / HISTONE DEACETYLASES / INHIBITION |