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Structure paper

TitleCrystal Structures of Trypanosoma Brucei Oligopeptidase B Broaden the Paradigm of Catalytic Regulation in Prolyl Oligopeptidase Family Enzymes.
Journal, issue, pagesPlos One, Vol. 8, Page 79349-, Year 2013
Publish dateMay 23, 2013 (structure data deposition date)
AuthorsCanning, P. / Rea, D. / Morty, R.E. / Fulop, V.
External linksPlos One / PubMed:24265767
MethodsX-ray diffraction
Resolution2.4 - 2.85 Å
Structure data

PDB-4bp8:
Oligopeptidase B from Trypanosoma brucei - open form
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-4bp9:
Oligopeptidase B from Trypanosoma brucei with covalently bound antipain - closed form
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei (eukaryote)
  • actinobacteria (actinobacteria)
KeywordsHYDROLASE / PROLYL OLIGOPEPTIDASE / CATALYTIC REGULATION / INDUCED FIT

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