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TitleStructural and Functional Perturbation of Giardia Lamblia Triosephosphate Isomerase by Modification of a Non-Catalytic, Non-Conserved Region.
Journal, issue, pagesPlos One, Vol. 8, Page 69031-, Year 2013
Publish dateApr 9, 2013 (structure data deposition date)
AuthorsHernandez-Alcantara, G. / Torres-Larios, A. / Enriquez-Flores, S. / Garcia-Torres, I. / Castillo-Villanueva, A. / Mendez, S.T. / De La Mora-De La Mora, I. / Gomez-Manzo, S. / Torres-Arroyo, A. / Lopez-Velazquez, G. ...Hernandez-Alcantara, G. / Torres-Larios, A. / Enriquez-Flores, S. / Garcia-Torres, I. / Castillo-Villanueva, A. / Mendez, S.T. / De La Mora-De La Mora, I. / Gomez-Manzo, S. / Torres-Arroyo, A. / Lopez-Velazquez, G. / Reyes-Vivas, H. / Oria-Hernandez, J.
External linksPlos One / PubMed:23894402
MethodsX-ray diffraction
Resolution1.45 - 2.7 Å
Structure data

PDB-4bi5:
CRYSTAL STRUCTURE OF A DOUBLE MUTANT (C202A AND C222D) OF TRIOSEPHOSPHATE ISOMERASE FROM GIARDIA LAMBLIA.
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4bi6:
CRYSTAL STRUCTURE OF A TRIPLE MUTANT (A198V, C202A AND C222N) OF TRIOSEPHOSPHATE ISOMERASE FROM GIARDIA LAMBLIA. COMPLEXED WITH 2- PHOSPHOGLYCOLIC ACID
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-4bi7:
CRYSTAL STRUCTURE OF A MUTANT (C202A) OF TRIOSEPHOSPHATE ISOMERASE FROM GIARDIA LAMBLIA COMPLEXED WITH 2-PHOSPHOGLYCOLIC ACID
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-PGA:
2-PHOSPHOGLYCOLIC ACID

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • giardia intestinalis (eukaryote)
KeywordsISOMERASE

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