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Structure paper

TitleStructural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 5229-, Year 2012
Publish dateJan 4, 2012 (structure data deposition date)
AuthorsMalito, E. / Bursulaya, B. / Chen, C. / Surdo, P.L. / Picchianti, M. / Balducci, E. / Biancucci, M. / Brock, A. / Berti, F. / Bottomley, M.J. ...Malito, E. / Bursulaya, B. / Chen, C. / Surdo, P.L. / Picchianti, M. / Balducci, E. / Biancucci, M. / Brock, A. / Berti, F. / Bottomley, M.J. / Nissum, M. / Costantino, P. / Rappuoli, R. / Spraggon, G.
External linksProc. Natl. Acad. Sci. USA / PubMed:22431623
MethodsX-ray diffraction
Resolution1.996 - 2.078 Å
Structure data

PDB-4ae0:
Crystal structure of diphtheria toxin mutant CRM197
Method: X-RAY DIFFRACTION / Resolution: 1.996 Å

PDB-4ae1:
Crystal structure of diphtheria toxin mutant CRM197 in complex with nicotinamide
Method: X-RAY DIFFRACTION / Resolution: 2.078 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NCA:
NICOTINAMIDE / medication*YM

Source
  • corynebacterium diphtheriae (bacteria)
KeywordsTOXIN

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