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| Title | Evolution of a designed retro-aldolase leads to complete active site remodeling. |
|---|---|
| Journal, issue, pages | Nat. Chem. Biol., Vol. 9, Page 494-498, Year 2013 |
| Publish date | Sep 23, 2011 (structure data deposition date) |
Authors | Giger, L. / Caner, S. / Obexer, R. / Kast, P. / Baker, D. / Ban, N. / Hilvert, D. |
External links | Nat. Chem. Biol. / PubMed:23748672 |
| Methods | X-ray diffraction |
| Resolution | 1.1 - 1.4 Å |
| Structure data | ![]() PDB-4a29: ![]() PDB-4a2r: ![]() PDB-4a2s: |
| Chemicals | ![]() ChemComp-3NK: ![]() ChemComp-MLT: ![]() ChemComp-HOH: |
| Source |
|
Keywords | DE NOVO PROTEIN / ENGINEERED ENZYME / RETRO-ALDOLASE / DIRECTED EVOLUTION / LYASE |
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sulfolobus solfataricus (archaea)
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