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TitleStructures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 70, Page 1015-, Year 2014
Publish dateDec 17, 2012 (structure data deposition date)
AuthorsJorgensen, R. / Batot, G. / Mannerstedt, K. / Imberty, A. / Breton, C. / Hindsgaul, O. / Royant, A. / Palcic, M.M.
External linksActa Crystallogr. ,Sect. F / PubMed:25084373
MethodsX-ray diffraction
Resolution1.701 - 1.9 Å
Structure data

PDB-3zgf:
Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with in complex with NPE caged UDP-Gal (P2(1)2(1)2(1) space group)
Method: X-RAY DIFFRACTION / Resolution: 1.701 Å

PDB-3zgg:
Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-SO4:
SULFATE ION

ChemComp-IUG:
1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / GLYCOSYLTRANSFERASES / CATALYTIC DOMAIN

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