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Structure paper

TitleStructures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 70, Page 553-564, Year 2014
Publish dateFeb 27, 2013 (structure data deposition date)
AuthorsYu, J. / Ogata, D. / Gai, Z. / Taguchi, S. / Tanaka, I. / Ooi, T. / Yao, M.
External linksActa Crystallogr. ,Sect. D / PubMed:24531489
MethodsX-ray diffraction
Resolution1.66 - 2.62 Å
Structure data

PDB-3w77:
Crystal Structure of azoreductase AzrA
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

PDB-3w78:
Crystal Structure of azoreductase AzrC in complex with NAD(P)-inhibitor Cibacron Blue
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

PDB-3w79:
Crystal Structure of azoreductase AzrC in complex with sulfone-modified azo dye Orange I
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3w7a:
Crystal Structure of azoreductase AzrC fin complex with sulfone-modified azo dye Acid Red 88
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-HOH:
WATER

ChemComp-CBD:
CIBACRON BLUE

ChemComp-ORI:
4-[(E)-(4-hydroxynaphthalen-1-yl)diazenyl]benzenesulfonic acid

ChemComp-RE8:
4-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonic acid

ChemComp-CA:
Unknown entry

ChemComp-K:
Unknown entry

Source
  • bacillus (Bacillus rRNA group 1)
KeywordsOXIDOREDUCTASE / azoreductase / azo bond cleavage / FMN-binding / OXIDOREDUCTASE/ OXIDOREDUCTASE INHIBITOR / OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR complex / azoreductase-azoreductase substrate complex

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