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-Structure paper
Title | High-resolution crystal structure of human protease-activated receptor 1 |
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Journal, issue, pages | Nature, Vol. 492, Page 387-392, Year 2012 |
Publish date | Aug 7, 2012 (structure data deposition date) |
Authors | Zhang, C. / Srinivasan, Y. / Arlow, D.H. / Fung, J.J. / Palmer, D. / Zheng, Y. / Green, H.F. / Pandey, A. / Dror, R.O. / Shaw, D.E. ...Zhang, C. / Srinivasan, Y. / Arlow, D.H. / Fung, J.J. / Palmer, D. / Zheng, Y. / Green, H.F. / Pandey, A. / Dror, R.O. / Shaw, D.E. / Weis, W.I. / Coughlin, S.R. / Kobilka, B.K. |
External links | Nature / PubMed:23222541 |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | PDB-3vw7: |
Chemicals | ChemComp-VPX: ChemComp-OLC: ChemComp-CL: ChemComp-NA: ChemComp-HOH: |
Source |
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Keywords | Signaling protein/antagonist / High resolution structure / protease-activated receptor 1 / inactive conformation / antagonist vorapaxar / G protein-coupled receptor / signaling protein / membrane protein / thrombin receptor-antagonist complex / Signaling protein-antagonist complex |