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Structure paper

TitleStructures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 69, Page 595-602, Year 2013
Publish dateJul 10, 2012 (structure data deposition date)
AuthorsNiwa, H. / Handa, N. / Tomabechi, Y. / Honda, K. / Toyama, M. / Ohsawa, N. / Shirouzu, M. / Kagechika, H. / Hirano, T. / Umehara, T. / Yokoyama, S.
External linksActa Crystallogr. ,Sect. D / PubMed:23519668
MethodsX-ray diffraction
Resolution2.001 - 2.5 Å
Structure data

PDB-3vuz:
Crystal structure of histone methyltransferase SET7/9 in complex with AAM-1
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3vv0:
Crystal structure of histone methyltransferase SET7/9 in complex with DAAM-3
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

Chemicals

ChemComp-K15:
5'-{[(3S)-3-amino-3-carboxypropyl](hexyl)amino}-5'-deoxyadenosine

ChemComp-HOH:
WATER

ChemComp-KH3:
5'-{[(3S)-3-amino-3-carboxypropyl][2-(hexylamino)ethyl]amino}-5'-deoxyadenosine

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / SET domain / transferase / adenosylmethionine binding / TRANSFERASE-TRANSFERASE INHIBITOR complex

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