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TitleStructural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
Journal, issue, pagesJ. Mol. Med., Year 2012
Publish dateDec 4, 2011 (structure data deposition date)
AuthorsOuyang, S. / Gong, B. / Li, J.-Z. / Zhao, L.-X. / Wu, W. / Zhang, F.-S. / Sun, L. / Wang, S.-J. / Pan, M. / Li, C. ...Ouyang, S. / Gong, B. / Li, J.-Z. / Zhao, L.-X. / Wu, W. / Zhang, F.-S. / Sun, L. / Wang, S.-J. / Pan, M. / Li, C. / Liang, W. / Shaw, N. / Zheng, J. / Zhao, G.-P. / Wang, Y. / Liu, Z.-J. / Liang, M.-F.
External linksJ. Mol. Med. / PubMed:22307521
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3ux9:
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE/IMMUNE SYSTEM / five helices / long loop connecting helix / hydrophobic interactions / CYTOKINE-IMMUNE SYSTEM complex

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