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Structure paper

TitleStructures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 212-219, Year 2012
Publish dateNov 23, 2011 (structure data deposition date)
AuthorsWang, H. / Elferich, J. / Gouaux, E.
External linksNat. Struct. Mol. Biol. / PubMed:22245965
MethodsX-ray diffraction
Resolution2.1 - 4.5 Å
Structure data

PDB-3usg:
Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 2.502 Å

PDB-3usi:
Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 3.106 Å

PDB-3usj:
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-3usk:
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 4.5 Å

PDB-3usl:
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-3usm:
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A)
Method: X-RAY DIFFRACTION / Resolution: 3.008 Å

PDB-3uso:
Crystal structure of LeuT bound to L-selenomethionine in space group P21212 from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 4.5 Å

PDB-3usp:
Crystal structure of LeuT in heptyl-beta-D-Selenoglucoside
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-LEU:
LEUCINE

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-UND:
UNDECANE

ChemComp-PC:
PHOSPHOCHOLINE

ChemComp-HOH:
WATER

ChemComp-MSE:
SELENOMETHIONINE

ChemComp-IOD:
IODIDE ION

ChemComp-CL:
Unknown entry

ChemComp-05L:
heptyl 1-seleno-beta-D-glucopyranoside

Source
  • aquifex aeolicus (bacteria)
KeywordsTRANSPORT PROTEIN / Leucine transporter

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