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-Structure paper
Title | HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. |
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Journal, issue, pages | ACS Med Chem Lett, Vol. 3, Page 402-406, Year 2012 |
Publish date | Aug 18, 2011 (structure data deposition date) |
Authors | Zhang, Y. / Lin, F.-Y. / Li, K. / Zhu, W. / Liu, Y.L. / Cao, R. / Pang, R. / Lee, E. / Axelson, J. / Hensler, M. ...Zhang, Y. / Lin, F.-Y. / Li, K. / Zhu, W. / Liu, Y.L. / Cao, R. / Pang, R. / Lee, E. / Axelson, J. / Hensler, M. / Wang, K. / Molohon, K.J. / Wang, Y. / Mitchell, D.A. / Nizet, V. / Oldfield, E. |
External links | ACS Med Chem Lett / PubMed:22662288 |
Methods | X-ray diffraction |
Resolution | 1.98 - 2.3 Å |
Structure data | PDB-3th8: PDB-4f6v: PDB-4f6x: |
Chemicals | ChemComp-TH9: ChemComp-HOH: ChemComp-ZYM: ChemComp-SRT: ChemComp-FJP: ChemComp-MG: ChemComp-ZYL: ChemComp-TAR: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / all helices / prenyl transferase / farneyl diphosphate binding / Isopentenyl diphosphate binding / prenylation / TRANSFERASE-TRANSFERASE INHIBITOR complex / TRANSFERASE / DEHYDROSQUALENE SYNTHASE / BPH-1034 / DIKETO ACID / VIRULENCE FACTOR / BPH-1112 |