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Structure paper

TitleCrystal structure of inhibitor of kappa B kinase beta.
Journal, issue, pagesNature, Vol. 472, Page 325-330, Year 2011
Publish dateJan 10, 2011 (structure data deposition date)
AuthorsXu, G. / Lo, Y.C. / Li, Q. / Napolitano, G. / Wu, X. / Jiang, X. / Dreano, M. / Karin, M. / Wu, H.
External linksNature / PubMed:21423167
MethodsX-ray diffraction
Resolution3.6 - 4 Å
Structure data

PDB-3qa8:
Crystal Structure of inhibitor of kappa B kinase beta
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-3rzf:
Crystal Structure of Inhibitor of kappaB kinase beta (I4122)
Method: X-RAY DIFFRACTION / Resolution: 4 Å

Chemicals

ChemComp-XNM:
(4-{[4-(4-chlorophenyl)pyrimidin-2-yl]amino}phenyl)[4-(2-hydroxyethyl)piperazin-1-yl]methanone

Source
  • xenopus laevis (African clawed frog)
KeywordsIMMUNE SYSTEM / SIGNALING PROTEIN / kinase ubiquitin-like domain / phosphorylation / kinase domain / ubiquitin-like domain / kinase / substrate binding / kinase uld / kinase ubiquitin-like domain scaffold helix / I kappa B alpha

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