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-Structure paper
Title | Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 133, Page 12474-12477, Year 2011 |
Publish date | Apr 28, 2011 (structure data deposition date) |
Authors | Cole, K.E. / Dowling, D.P. / Boone, M.A. / Phillips, A.J. / Christianson, D.W. |
External links | J. Am. Chem. Soc. / PubMed:21790156 |
Methods | X-ray diffraction |
Resolution | 2.143 Å |
Structure data | PDB-3rqd: |
Chemicals | ChemComp-ZN: ChemComp-K: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / histone deacetylase / largazole / histone deacetylation / HYDROLASE-HYDROLASE INHIBITOR complex |