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TitleStructural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains.
Journal, issue, pagesChem. Biol., Vol. 19, Page 188-198, Year 2012
Publish dateApr 7, 2011 (structure data deposition date)
AuthorsSundlov, J.A. / Shi, C. / Wilson, D.J. / Aldrich, C.C. / Gulick, A.M.
External linksChem. Biol. / PubMed:22365602
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-3rg2:
Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-SVS:
5'-deoxy-5'-({[2-(2-hydroxyphenyl)ethyl]sulfonyl}amino)adenosine

ChemComp-PNS:
4'-PHOSPHOPANTETHEINE

ChemComp-IOD:
IODIDE ION

Source
  • escherichia coli (E. coli)
KeywordsLIGASE / Adenylate-forming enzymes / ANL Superfamily / Non-ribosomal peptide synthetase carrier protein Function / NRPS adenylation domain acyl carrier protein / 4'phosphopantetheinylation 4'PP cofactor

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