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-Structure paper
Title | Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 108, Page 8628-8633, Year 2011 |
Publish date | Nov 16, 2010 (structure data deposition date) |
Authors | Zarpellon, A. / Celikel, R. / Roberts, J.R. / McClintock, R.A. / Mendolicchio, G.L. / Moore, K.L. / Jing, H. / Varughese, K.I. / Ruggeri, Z.M. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:21555542 |
Methods | X-ray diffraction |
Resolution | 3.2 Å |
Structure data | PDB-3pmh: |
Chemicals | ChemComp-0G7: ChemComp-NAG: |
Source |
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Keywords | blood cloting / hydrolase/inhibitor / Sulfated tyrosine residues / Leucine Rich Repeats / Protease Platelet receptor of thrombin / Thrombin binding / Platelet surface / hydrolase-inhibitor complex |