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Structure paper

TitleCo-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Journal, issue, pagesPlos One, Vol. 6, Page e18413-e18413, Year 2011
Publish dateAug 10, 2010 (structure data deposition date)
AuthorsKim, J.J. / Casteel, D.E. / Huang, G. / Kwon, T.H. / Ren, R.K. / Zwart, P. / Headd, J.J. / Brown, N.G. / Chow, D.C. / Palzkill, T. / Kim, C.
External linksPlos One / PubMed:21526164
MethodsX-ray diffraction
Resolution2.49 - 2.9 Å
Structure data

PDB-3ocp:
Crystal structure of cAMP bound cGMP-dependent protein kinase(92-227)
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

PDB-3od0:
Crystal structure of cGMP bound cGMP-dependent protein kinase(92-227)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3ogj:
Crystal structure of partial apo (92-227) of cGMP-dependent protein kinase
Method: X-RAY DIFFRACTION / Resolution: 2.751 Å

Chemicals

ChemComp-CMP:
ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-PCG:
CYCLIC GUANOSINE MONOPHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / serine/threonine kinase / TF2I and IRAG

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