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TitleInaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 108, Page 903-910, Year 2011
Publish dateJul 24, 2010 (structure data deposition date)
AuthorsTian, Y. / Simanshu, D.K. / Ma, J.B. / Patel, D.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:21193640
MethodsX-ray diffraction
Resolution2.1 - 2.9248 Å
Structure data

PDB-3o3i:
Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OH at its 3'-end
Method: X-RAY DIFFRACTION / Resolution: 2.801 Å

PDB-3o6e:
Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OCH3 at its 3'-end
Method: X-RAY DIFFRACTION / Resolution: 2.904 Å

PDB-3o7v:
Crystal Structure of human Hiwi1 (V361M) PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OCH3 at its 3'-end
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3o7x:
Crystal structure of human Hili PAZ domain
Method: X-RAY DIFFRACTION / Resolution: 2.9248 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Piwi / PAZ / RNA silencing / pi-RNA / Hiwi1 / Hili / PAZ domain / RNA BINDING PROTEIN/RNA / RNA BINDING PROTEIN-RNA complex

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