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-Structure paper
Title | The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. |
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Journal, issue, pages | J. Biol. Chem., Vol. 291, Page 7256-7266, Year 2016 |
Publish date | Apr 21, 2010 (structure data deposition date) |
Authors | Ho, N.A. / Dawes, S.S. / Crowe, A.M. / Casabon, I. / Gao, C. / Kendall, S.L. / Baker, E.N. / Eltis, L.D. / Lott, J.S. |
External links | J. Biol. Chem. / PubMed:26858250 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.6 Å |
Structure data | PDB-3mnl: PDB-5cw8: PDB-5cxg: PDB-5cxi: |
Chemicals | ChemComp-PGE: ChemComp-HOH: ChemComp-55X: ChemComp-PEG: ChemComp-5TW: |
Source |
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Keywords | TRANSCRIPTION REGULATOR / tetR family of transcriptional regulator / all-helical / DNA-binding / hydrophobic ligand-binding / Structural Genomics / TB Structural Genomics Consortium / TBSGC / Transcriptional repressor / TetR family Transcriptional repressor / cholesterol catabolism / CoA thioester ligand / TRANSCRIPTION / TetR family Tcholesterol catabolism |