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TitleStructural basis of telomeric RNA quadruplex-acridine ligand recognition.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 133, Page 2721-2728, Year 2011
Publish dateApr 10, 2010 (structure data deposition date)
AuthorsCollie, G.W. / Sparapani, S. / Parkinson, G.N. / Neidle, S.
External linksJ. Am. Chem. Soc. / PubMed:21291211
MethodsX-ray diffraction
Resolution2.6 - 3.2 Å
Structure data

PDB-3mij:
Crystal structure of a telomeric RNA G-quadruplex complexed with an acridine-based ligand.
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3qcr:
Incomplete structural model of a human telomeric DNA quadruplex-acridine complex.
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-R14:
N,N'-[acridine-3,6-diylbis(1H-1,2,3-triazole-1,4-diylbenzene-3,1-diyl)]bis[3-(diethylamino)propanamide]

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA / Quadruplex / RNA-ligand complex / telomeric / DNA / acridine ligand-complex / telomere

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