+Search query
-Structure paper
Title | Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 1985-1989, Year 2010 |
Publish date | Jan 7, 2010 (structure data deposition date) |
![]() | Lesuisse, D. / Dutruc-Rosset, G. / Tiraboschi, G. / Dreyer, M.K. / Maignan, S. / Chevalier, A. / Halley, F. / Bertrand, P. / Burgevin, M.C. / Quarteronet, D. / Rooney, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.03 - 2.4 Å |
Structure data | ![]() PDB-3lau: ![]() PDB-3lfn: ![]() PDB-3lfq: ![]() PDB-3lfs: |
Chemicals | ![]() ChemComp-OFI: ![]() ChemComp-HOH: ![]() ChemComp-A27: ![]() ChemComp-A28: ![]() ChemComp-A07: |
Source |
|
![]() | TRANSFERASE / Kinase inhibitor complex / ATP-binding / Cell cycle / Cytoplasm / Cytoskeleton / Kinase / Nucleotide-binding / Phosphoprotein / Polymorphism / Serine/threonine-protein kinase / Ubl conjugation / protein kinase fold / Acetylation / Cell division / Mitosis |