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Structure paper

TitleStructures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.
Journal, issue, pagesFebs J., Vol. 278, Page 793-808, Year 2011
Publish dateOct 13, 2009 (structure data deposition date)
AuthorsStern, A.L. / Naworyta, A. / Cazzulo, J.J. / Mowbray, S.L.
External linksFebs J. / PubMed:21205211
MethodsX-ray diffraction
Resolution1.4 - 2.2 Å
Structure data

PDB-3k7o:
Structure of type B ribose 5-phosphate isomerase from Trypanosoma cruzi
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3k7p:
Structure of mutant of ribose 5-phosphate isomerase type B from Trypanosoma cruzi.
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-3k7s:
Complex of Trypanosoma cruzi ribose 5-phosphate isomerase type B with ribose 5-phosphate
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3k8c:
Complex of Trypanosoma cruzi ribose 5-phosphate isomerase type B with 4-deoxy-4-phospho-D-erythronohydroxamic acid
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3m1p:
Structure of ribose 5-phosphate isomerase type B from Trypanosoma cruzi, soaked with allose-6-phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-R52:
5-O-phosphono-D-ribose

ChemComp-RES:
4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID

Source
  • trypanosoma cruzi (eukaryote)
KeywordsISOMERASE / pentose phosphate pathway / Type B ribose 5-phosphate isomerase (RpiB) / R5P / phosphate / 4PEH / 4-deoxy-4-phospho-D-erythronohydroxamic acid / type B ribose 5-phosphate isomerase / allose-6-phosphate

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