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-Structure paper
Title | Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new pim kinase inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 52, Page 6369-6381, Year 2009 |
Publish date | Sep 4, 2009 (structure data deposition date) |
Authors | Akue-Gedu, R. / Rossignol, E. / Azzaro, S. / Knapp, S. / Filippakopoulos, P. / Bullock, A.N. / Bain, J. / Cohen, P. / Prudhomme, M. / Anizon, F. / Moreau, P. |
External links | J. Med. Chem. / PubMed:19788246 |
Methods | X-ray diffraction |
Resolution | 2.35 Å |
Structure data | PDB-3jpv: |
Chemicals | ChemComp-1DR: ChemComp-HOH: |
Source |
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Keywords | transferase / transferase inhibitor / oncogene / kinase / serine-threonine / PIM1 / pyrrolo[2 / 3-a]carbazole / Structural Genomics Consortium / SGC / Alternative initiation / ATP-binding / Cell membrane / Manganese / Membrane / Metal-binding / Nucleotide-binding / Nucleus / Phosphoprotein / Proto-oncogene / Serine/threonine-protein kinase / Transferase / transferase - transferase inhibitor COMPLEX |