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-Structure paper
Title | Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2. |
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Journal, issue, pages | Plos One, Vol. 4, Page e6613-e6613, Year 2009 |
Publish date | Jun 24, 2009 (structure data deposition date) |
Authors | Gordon, W.R. / Vardar-Ulu, D. / L'Heureux, S. / Ashworth, T. / Malecki, M.J. / Sanchez-Irizarry, C. / McArthur, D.G. / Histen, G. / Mitchell, J.L. / Aster, J.C. / Blacklow, S.C. |
External links | Plos One / PubMed:19701457 |
Methods | X-ray diffraction |
Resolution | 3.2 Å |
Structure data | PDB-3i08: |
Chemicals | ChemComp-CA: ChemComp-CL: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN / SEA domain / Lin-12 Notch repeat / LNR / Heterodimerization Domain / HD / Activator / ANK repeat / Calcium / Cell membrane / Developmental protein / Differentiation / Disulfide bond / EGF-like domain / Glycoprotein / Membrane / Metal-binding / Notch signaling pathway / Nucleus / Phosphoprotein / Polymorphism / Receptor / Transcription / Transcription regulation / Transmembrane / furin / T-ALL / leukemia / oncogene / metalloprotease / gamma-secretase |